Degree-Based Molecular Descriptors and QSPR Analysis of Breast Cancer Drugs
نویسندگان
چکیده
The disease that involves abnormal cell growth and spreads through the surrounding tissues damaging other parts of body is cancer. Breast cancer most common one out many types. Women are affected by breast either hormonal changes or genetic occur in DNA. As a life-threatening disease, it necessary for further studies to gear up fighting deadliest disease. In this work, detailed study made on occurrence, symptoms, drugs involved its treatment. For purpose, quantitative structure-property relationship (QSPR) analysis using 21 used treatment considered modelled as molecular graphs their structures, 11 topological indices computed. QSPR carried these drugs, conclusions drawn based analysis.
منابع مشابه
Molecular imaging approaches in the diagnosis of breast cancer: A systematic review and meta-analysis
Introduction:The accuracy of positron emission tomography with computed tomography (PET/CT), positron emission mammography (PEM), and breast specific-gamma imaging (BSGI) in diagnosing breast cancer has never been systematically assessed, the present systematic review was aimed to address this issue. Methods:PubMed, Scopus and EMBASE were searched for st...
متن کاملModified and enhanced replacement method for the selection of molecular descriptors in QSAR and QSPR theories
Article history: Received 9 January 2008 Received in revised form 13 February 2008 Accepted 17 February 2008 Available online 29 February 2008 We improve a recently developed Replacement Method (RM) for the selection of an optimal set of molecular descriptors from a much greater pool of such regression variables. Our approach yields almost optimal results with a much smaller number of linear re...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولTraditional topological indexes vs electronic, geometrical, and combined molecular descriptors in QSAR/QSPR research
A comparison of the performance of molecular descriptors of different types was conducted. The study was concentrated on determining which descriptors are included in the best linear multivariate regression models constructed for modeling various physicochemical properties (melting point, boiling point, refractive index, molar volume, and density) and biological activities (anaesthetic activity...
متن کاملMolecular Epidemiology of Breast Cancer among Iranian-Azeri Population based on P53 Research
Background: This study was done in order to enhance our understanding about molecular and epidemiological features of breast cancer among the Azeri population with special emphasis on the detection of TP53 mutations. We also analyzed the role of the P53codon72 polymorphism (rs1042522) and its role in susceptibility to breast cancer. Methods: ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Mathematics
سال: 2022
ISSN: ['2314-4785', '2314-4629']
DOI: https://doi.org/10.1155/2022/5880011